Anti-LRRC8C Antilichaam

LRRC8C (Leucine-rich repeat-containing protein 8C), also known as AD158, is a non-essential component of the volume-regulated anion channel (VRAC, also known as VSOAC channel), which is required to maintain a constant cell volume in response to extracellular or intracellular permeability changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. The VRAC channel also mediates transport of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response to DNA virus in the cytosol (PMID:24790029; 26824658; 28193731) .

Boster Bio Anti-LRRC8C Antibody catalog # A10344. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Volume-regulated anion channel subunit LRRC8C; Leucine-rich repeat-containing protein 8C; FAD158; AD158

LRRC8C

Q8TDW0

Human, Mouse, Rat

E.coli-derived human LRRC8C recombinant protein (Position: K620-K801) .

WB, IHC, ICC, IF, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10344

Leucine rich repeat containing 8 VRAC subunit C

Volume-regulated anion channel subunit LRRC8C

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.