Anti-LSR Antibody Picoband® 31.0550 Vervoeging

Lipolysis-stimulated lipoprotein receptor is a protein that in humans is encoded by the LSR gene. LSR has a probable role in the clearance of triglyceride-rich lipoprotein from blood. It binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.

Platelet basic protein; PBP; C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF; Macrophage-derived growth factor; MDGF; Small-inducible cytokine B7; PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1; NAP-2

LSR

51599

Q86X29

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human LSR recombinant protein (Position: K16-E633) .

Flow Cytometry

Cardiovascular, Chemokines, Immunology, Innate Immunity, Platelets

Immunogen affinity purified.

Liquid

LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2 (73), NAP-2 (74), NAP-2 (1-66), and most potent NAP-2 (1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III (1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

1. Gross, M. B. Personal Communication. Baltimore, Md. 9/30/2015. 2. Hemmasi, S., Czulkies, B. A., Schorch, B., Veit, A., Aktories, K., Papatheodorou, P. Interaction of the Clostridium difficile binary toxin CDT and its host cell receptor, lipolysis-stimulated lipoprotein receptor (LSR) . J. Biol. Chem. 290: 14031-14044, 2015. 3. Masuda, S., Oda, Y., Sasaki, H., Ikenouchi, J., Higashi, T., Akashi, M., Nishi, E., Furuse, M. LSR defines cell corners for tricellular tight junction formation in epithelial cells. J. Cell Sci. 124: 548-555, 2011.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

12252 MW

6

Neutrophil-activating peptide 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.