Anti-LTBR Antibody Picoband®

LTBR (Lymphotoxin B Receptor), also called TNFCR or LT-BETA-R, is a receptor for lymphotoxin which in humans is encoded by the LTBR gene. By linkage analysis with recombinant inbred mouse strains, Nakamura et al. (1995) demonstrated that the Tnfcr locus is close to the Tnfr1 gene on mouse chromosome 6. Presumably, the human homolog is located on 12p13. Silva-Santos et al. (2005) reported that double-positive T cells regulate the differentiation of early thymocyte progenitors and gamma-delta cells by a mechanism dependent on the transcription factor ROR-gamma-t and the lymphotoxin-beta receptor. Lo et al. (2007) identified lymphotoxin and LIGHT (TNFSF14), tumor necrosis factor cytokine family members that are primarily expressed on lymphocytes, as critical regulators of key enzymes that control lipid metabolism.

Boster Bio Anti-LTBR Antibody Picoband® catalog # A00942-2. Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

LTBR

4055

P36941

Human

E.coli-derived human LTBR recombinant protein (Position: Q31-Q404) . Human LTBR shares 67% amino acid (aa) sequence identity with mouse LTBR.

WB, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Lo, J. C., Wang, Y., Tumanov, A. V., Bamji, M., Yao, Z., Reardon, C. A., Getz, G. S., Fu, Y.-X. Lymphotoxin beta receptor-dependent control of lipid homeostasis. Science 316: 285-288, 2007. 2. Nakamura, T., Tashiro, K., Nazarea, M., Nakano, T., Sasayama, S., Honjo, T. The murine lymphotoxin-beta receptor cDNA: isolation by the signal sequence trap and chromosomal mapping. Genomics 30: 312-319, 1995. 3. Silva-Santos, B., Pennington, D. J., Hayday, A. C. Lymphotoxin-mediated regulation of gamma-delta cell differentiation by alpha-beta T cell progenitors. Science 307: 925-928, 2005.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A00942-2

55-60 kDa

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.