Anti-LY6D Antibody Picoband® 31.0550 Vervoeging

LY6D, also named as E48 and ThB, may act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. It marks the earliest stage of B-cell specification.

LY6D

8581

Q14210

Human

E.coli-derived human LY6D recombinant protein (Position: L21-L111) . Human LY6D shares 60.4% amino acid (aa) sequence identity with mouse LY6D.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Brakenhoff, R. H., Gerretsen, M., Knippels, E. M. C., van Dijk, M., van Essen, H., Weghuis, D. O., Sinke, R. J., Snow, G. B., van Dongen, G. A. M. S. The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion. J. Cell Biol. 129: 1677-1689, 1995. 2. Brakenhoff, R. H., van Dijk, M., Rood-Knippels, E. M. C., Snow, G. B. A gain of novel tissue specificity in the human Ly-6 gene E48. J. Immun. 159: 4879-4886, 1997. 3. Inlay, M. A., Bhattacharya, D., Sahoo, D., Serwold, T., Seita, J., Karsunky, H., Plevritis, S. K., Dill, D. L., Weissman, I. L. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 23: 2376-2381, 2009. Note: Erratum: Genes Dev. 27: 2063 only, 2013.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.