Anti-LYRM4 Antibody Picoband® fluoro594 Vervoeging

The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis.

LYRM4

57128

Q9HD34

Human, Mouse, Rat

E.coli-derived human LYRM4 recombinant protein (Position: M1-T91) . Human LYRM4 shares 89% amino acid (aa) sequence identity with mouse LYRM4.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Adam, A. C., Bornhovd, C., Prokisch, H., Neupert, W., Hell, K. The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J. 25: 174-183, 2006. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 3/17/2010. 3. Lim, S. C., Friemel, M., Marum, J. E., Tucker, E. J., Bruno, D. L., Riley, L. G., Christodoulou, J., Kirk, E. P., Boneh, A., DeGennaro, C. M., Springer, M., Mootha, V. K., Rouault, T. A., Leimkuhler, S., Thorburn, D. R., Compton, A. G. Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. Hum. Molec. Genet. 22: 4460-4473, 2013.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.