Anti-MAD2L2 Antibody Picoband® fluoro647 Vervoeging

Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene. The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.

Calcitonin; Calca; Calc

MAD2L2

10459

Q9UI95

Human

No cross-reactivity with other proteins.

E.coli-derived human MAD2L2 recombinant protein (Position: M1-K209) .

Flow Cytometry

Cardiovascular, Contractility, Neuropeptides, Neuroscience, Neurotransmitter, Vasculature

Immunogen affinity purified.

Liquid

Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

1. Bluteau, D., Masliah-Planchon, J., Clairmont, C., Rousseau, A., Ceccaldi, R., Dubois d'Enghien, C., Bluteau, O., Cuccuini, W., Gachet, S., Peffault de Latour, R., Leblanc, T., Socie, G., Baruchel, A., Stoppa-Lyonnet, D., D'Andrea, A. D., Soulier, J. Biallelic inactivation of REV7 is associated with Fanconi anemia. J. Clin. Invest. 126: 3580-3584, 2016. Note: Erratum: J. Clin. Invest. 127: 1117 only, 2017. 2. Boersma, V., Moatti, N., Segura-Bayona, S., Peuscher, M. H., van der Torre, J., Wevers, B. A., Orthwein, A., Durocher, D., Jacobs, J. J. L. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5-prime end resection. Nature 521: 537-540, 2015. 3. Cahill, D. P., da Costa, L. T., Carson-Walter, E. B., Kinzler, K. W., Vogelstein, B., Lengauer, C. Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics 58: 181-187, 1999.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Calcitonin/calcitonin-related polypeptide, alpha

Secreted.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.