Anti-MALT1 Konijn Monoklonale Antilichaam

Boster Bio Anti-MALT1 Rabbit Monoclonal Antibody catalog # M01599-2. Tested in WB, ICC/IF applications. This antibody reacts with Human.

E3 ubiquitin-protein ligase NEDD4-like;6.3.2.-; NEDD4.2; Nedd4-2; NEDD4L; KIAA0439, NEDL3

MALT1

10892

Q9UDY8

Human

A synthesized peptide derived from human MALT1

Clone: 23M89

Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597) . Expressed in melanocytes (PubMed:23999003) . .

WB, ICC, IF

Apoptosis, Caspases, Cell Biology, Intracellular, NFKB Pathway, Nuclear Signaling, Signal Transduction, Signaling Pathway

Affinity-chromatography

0.5mg/ml

Liquid

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01599-2

111932 MW

92 kDa

E3 ubiquitin-protein ligase NEDD4-like

Cytoplasm . May be recruited to exosomes by NDFIP1.

Lysosome-associated membrane glycoprotein 2 (Lamp2)

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.