Anti-MAP1LC3C Antilichaam

FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes) . SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: LC3-I: Cytoplasm. LC3-II: Intracytoplasmic membrane; lipid-anchor. LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. PTM: The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. SIMILARITY: Belongs to the MAP1 LC3 family.

Our Anti-Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) rabbit polyclonal primary antibody detects human Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C), and is whole serum. It is validated for use in ICC, IHC-Frozen, WB.

Our Anti-Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) rabbit polyclonal primary antibody detects human Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C), and is whole serum. It is validated for use in ICC, IHC-Frozen, WB.

Microtubule-associated proteins 1A/1B light chain 3C; Microtubule-associated protein 1 light chain 3 gamma; MAP1A/MAP1B LC3 C; MAP1A/1B light chain 3 C; MAP1 light chain 3-like protein 3; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; APG8c; MAP1LC3C

Q9BXW4

Human

A synthetic peptide (CQEEVAGIRAKF) corresponding to the N-terminal of human MAP1LC3 C conjugated to Blue Carrier Protein has been used as the immunogen. The peptide is homologous with the corresponding sequence deriven from MAP1LC3 C protein in Macaca mulatta (monkey) and Canis familiaris (dog) .

Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C)

Unconjugated

ICC, IHC-Frozen, WB

Whole serum

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

1:100-1:1000

1:100-1:1000

IHC and WB confirmed the specificity for MAP1LC3 C. This antibody should recognize MAP1LC3 C only and not the other forms MAP1LC3A and MAP1LC3B. Human, other species have not yet been tested.

Rabbit

Lyophilized

Mixed

Human