Anti-MARCO Antibody Picoband® APC-vervoeging

Macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene.

MARCO; SCARA2; Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2

MARCO

8685

Q9UEW3

Human

No cross-reactivity with other proteins

E.coli-derived human MARCO recombinant protein (Position: M1-R489) . Human MARCO shares 66.5% amino acid (aa) sequence identity with mouse MARCO.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Arredouani, M., Yang, Z., Ning, Y. Y., Qin, G., Soininen, R., Tryggvason, K., Kobzik, L. The scavenger receptor MARCO is required for lung defense against Pneumococcal pneumonia and inhaled particles. J. Exp. Med. 200: 267-272, 2004. 2. Dorrington, M. G., Roche, A. M., Chauvin, S. E., Tu, Z., Mossman, K. L., Weiser, J. N., Bowdish, D. M. E. MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. J. Immun. 190: 250-258, 2013. 3. Elomaa, O., Kangas, M., Sahlberg, C., Tuukkanen, J., Sormunen, R., Liakka, A., Thesleff, I., Kraal, G., Tryggvason, K. Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell 80: 603-609, 1995.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

53 kDa

6

Macrophage receptor MARCO

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.