Anti-Mast Cell Tryptase Rabbit Monoklonale Antilichaam

Boster Bio Anti-Mast Cell Tryptase Rabbit Monoclonal Antibody catalog # M08039. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Tryptase alpha/beta-1; Tryptase-1;3.4.21.59; Tryptase I; Tryptase alpha-1; TPSAB1; TPS1, TPS2, TPSB1

TPSAB1

7177

Q15661

Human, Mouse, Rat

A synthesized peptide derived from human Mast Cell Tryptase

Clone: FHH-20

Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level) . .

WB, IHC, IP

Amino Acid Metabolism, Amino Acids, Cancer, Immunology, Innate Immunity, Macrophage/Inflammation, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M08039

30515 MW

100 kDa

Tryptase alpha/beta-1

Secreted. Released from the secretory granules upon mast cell activation. .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.