Anti-MAT2A Antibody Picoband®

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.

Boster Bio Anti-MAT2A Antibody Picoband® catalog # A04557-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1; Xcl1; Lptn; Ltn; Scyc1

MAT2A

4144

P31153

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human MAT2A recombinant protein (Position: M1-A229) .

Expressed in activated CD8 (+) T cells. In the thymus, expressed by medullary thymic epithelial cells.

WB, IHC, Flow Cytometry, ELISA

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.

1. Chamberlin, M. E., Ubagai, T., Mudd, S. H., Wilson, W. G., Leonard, J. V., Chou, J. Y. Demyelination of the brain is associated with methionine adenosyltransferase I/III deficiency. J. Clin. Invest. 98: 1021-1027, 1996. 2. De La Rosa, J., Ostrowski, J., Hryniewicz, M. M., Kredich, N. M., Kotb, M., LeGros, H. L., Jr., Valentine, M., Geller, A. M. Chromosomal localization and catalytic properties of the recombinant alpha subunit of human lymphocyte methionine adenosyltransferase. J. Biol. Chem. 270: 21860-21868, 1995. 3. Guo, D., Gong, L., Regalado, E. S., Santos-Cortez, R. L., Zhao, R., Cai, B., Veeraraghavan, S., Prakash, S. K., Johnson, R. J., Muilenburg, A., Willing, M., Jondeau, G., and 14 others. MAT2A mutations predispose individuals to thoracic aortic aneurysms. Am. J. Hum. Genet. 96: 170-177, 2015.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A04557-1

50 kDa

6

Chemokine (C motif) ligand 1

Secreted.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.