Anti-MDFI (P134) Antilichaam

Boster Bio Anti-MDFI (P134) Antibody catalog # A10664. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

MyoD family inhibitor; Myogenic repressor I-mf; MDFI

MDFI

Q99750

Human, Mouse, Rat

Synthetic peptide, corresponding to amino acids 100-146 of Human MDFI.

WB, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10664

25029 MW

MyoD family inhibitor

Nucleus . Cytoplasm .

MyoD family inhibitor

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2