Anti-ME1 Antibody Picoband® 0,00647 Vervoeging

NADP-dependent malic enzyme is a protein that in humans is encoded by the ME1 gene. This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; SLC31A1; COPT1; CTR1

ME1

4199

P48163

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human ME1 recombinant protein (Position: M1-Q572) .

Found in the synovial fluid of patients with rheumatoid arthritis. .

Flow Cytometry

Neuroscience, Neurotransmission, Receptors / Channels

Immunogen affinity purified.

Liquid

High-affinity, saturable copper transporter involved in dietary copper uptake.

1. Chen, T.-R., McMorris, F. A., Creagan, R., Ricciuti, F. C., Tischfield, J., Ruddle, F. H. Assignment of the genes for malate oxidoreductase decarboxylating to chromosome 6 and peptidase B and lactate dehydrogenase B to chromosome 12 in man. Am. J. Hum. Genet. 25: 200-207, 1973. 2. Cohen, P. T. W., Omenn, G. S. Genetic variation of the cytoplasmic and mitochondrial malic enzymes in the monkey: Macaca nemestrina. Biochem. Genet. 7: 289-301, 1972. 3. Gimelbrant, A., Hutchinson, J. N., Thompson, B. R., Chess, A. Widespread monoallelic expression on human autosomes. Science 318: 1136-1140, 2007.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

64 kDa

6

Solute carrier family 31 member 1

Cell membrane; Localizes to the apical membrane in intestinal epithelial cells.

Tumor necrosis factor-inducible gene 6 protein

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.