Anti-Metalloreductase STEAP2 STEAP2 Antilichaam

The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.

Boster Bio Anti-Metalloreductase STEAP2 STEAP2 Antibody (Catalog # A08410) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

STMP, IPCA1, PUMPCn, STAMP1, PCANAP1, UNQ6507/PRO23203, Metalloreductase STEAP2, Prostate cancer-associated protein 1

STEAP2

Q8NFT2

Human, Mouse

This STEAP2 antibody does not cross-react with other STEAP proteins.

STEAP2 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human STEAP2. The immunogen is located within the last 50 amino acids of STEAP2.

Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.

ELISA, WB, IHC-P, IF

Homeostasis

STEAP2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+) . Uses NAD (+) as acceptor (By similarity) . .

STEAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A08410

56056 MW

Six transmembrane epithelial antigen of the prostate 2

Endosome membrane ; Multi-pass membrane protein . Cell membrane

Six transmembrane epithelial antigen of the prostate 2

IgG

STEAP2 Antibody is supplied in PBS containing 0.02% sodium azide.