Anti-MGAM Antibody Picoband® fluoro488 Vervoeging

Maltase-glucoamylase, intestinal is an enzyme that in humans is encoded by the MGAM gene. This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities.

Mesoderm posterior protein 1; Class C basic helix-loop-helix protein 5; bHLHc5; MESP1; BHLHC5

MGAM

8972

O43451

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human MGAM recombinant protein (Position: Y131-I2697) .

Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .

Flow Cytometry

Interleukins

Immunogen affinity purified.

Liquid

Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.

1. Naim, H. Y., Sterchi, E. E., Lentze, M. J. Structure, biosynthesis, and glycosylation of human small intestinal maltase-glucoamylase. J. Biol. Chem. 263: 19709-19717, 1988. 2. Nichols, B. L., Avery, S., Sen, P., Swallow, D. M., Hahn, D., Sterchi, E. The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities. Proc. Nat. Acad. Sci. 100: 1432-1437, 2003. 3. Nichols, B. L., Eldering, J., Avery, S., Hahn, D., Quaroni, A., Sterchi, E. Human small intestinal maltase-glucoamylase cDNA cloning: homology to sucrase-isomaltase. J. Biol. Chem. 273: 3076-3081, 1998.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

108320 MW

6

Mesoderm posterior bHLH transcription factor 1

Nucleus.

Gamma-aminobutyric acid type B receptor subunit 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.