Anti-MI/R letselverwekker 1

Anti-MI/R injury agent 1 (compound 18), a Panaxatriol derivative, is an orally active, potent anti-myocardial ischemia/reperfusion (anti-MI/R) injury agent. Anti-MI/R injury agent 1 enhances oxygen-glucose deprivation and reperfusion (OGD/R) -induced cardiomyocyte injury cell viability. Anti-MI/R injury agent 1 can markedly reduce myocardial infarction size, decrease circulating cardiac troponin I (cTnI) leakage, and alleviate cardiac tissue damage in the rats[1].

2387506-35-4

12352005

Others

Reference compound

Others

Neuroscience-Neuromodulation

Cardiovascular Disease

https://www.medchemexpress.com/anti-mi-r-injury-agent-1.html

10 mM in DMSO

CC1(C)C2=C(C(C(O)=O)=NO2)C[C@@]3(C)C1[C@@H](O)C[C@]4(C)C3C[C@@H](O)C5[C@@]4(C)CC[C@]5([H])[C@@]6(C)CCCC(C)(C)O6

C32H49NO6

543.73

[1]Qiong Wu, et al. Synthesis and biological evaluation of panaxatriol derivatives against myocardial ischemia/reperfusion injury in the rat. Eur J Med Chem. 2020 Jan 1;185:111729.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-130272/

Reference compound1

No Development Reported