Anti-microtubule-geassocieerde eiwitten 1A/1B lichtketen 3A (MAP1LC3A) Antilichaam

MAP1A and MAP1B are microtubule-associated protein which mediate the physical interactions between microtubules and components of the cytoskeleton (probably involved in autophagosome formation) . MAP1A and MAP1B each consist of a heavy chain subunit and 3 different light chain subunits (LC1, LC2 and LC3) . MAP1LC3A is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor form of MAP1LC3A is cleaved by APG4/ATG4B to form the cytosolic form LC3-1. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. MAP1LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but is absent in thymus and peripheral leukocytes.

Our Anti-Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A) rabbit polyclonal primary antibody detects human and rat Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A), and is whole serum. It is validated for use in ICC, WB.

Our Anti-Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A) rabbit polyclonal primary antibody detects human and rat Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A), and is whole serum. It is validated for use in ICC, WB.

Microtubule-associated proteins 1A/1B light chain 3A; MAP1A/MAP1B LC3 A; MAP1A/1B light chain 3 A; MAP1 light chain 3-like protein 1; Microtubule-associated protein 1 light chain 3 alpha; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; APG8a; MAP1LC3A

Q9H492

Human and Rat

A synthetic peptide (RSFADRCKEVQQI) corresponding to the N-terminal of human MAP1LC3 A protein conjugated to Blue Carrier Protein has been used as the immunogen. The sequence is homologous with mouse and rat MAP1LC3 A.

Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A)

Unconjugated

ICC, WB

Whole serum

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

1:100-1:1000

0.3888888888888889

IHC, WB and ELISA confirmed the specificity for MAP1LC3 A. Human, rat. Other species not yet tested.

1:100-1:1000

Rabbit

Lyophilized

Mixed

Human