Anti-MIG/CXCL9 Antibody Picoband®

MIG, also known as CXCL9, is a T-cell chemoattractant inducible by gamma interferon that is a member of the CXC chemokine family of cytokines. This gene is mapped to 4q21. It is noted that, although the best-described activities of the chemokines are as chemotactic factors, chemokines also have an effect on T-cell activation, angiogenesis, and HIV infection. While most CXC chemokines are chemotactic for neutrophils, MIG and INP10 are unusual and similar in being CXC chemokines that are chemotactic for lymphocytes and inactive in neutrophils.

Boster Bio Anti-MIG/CXCL9 Antibody catalog # PA1429. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

C-X-C motif chemokine 9; Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9; CXCL9; CMK, MIG, SCYB9

CXCL9

4283

Q07325

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human CXCL9.

Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands. Moderate levels found in thymus, ovary and small intestine. Not detected in salivary gland, muscle or liver. Also expressed in cell lines of myeloid, fibroblast and epithelial origin. Not detected in most lymphoid cell lines. .

IHC, WB

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.

1. Lee HH, Farber JM (1996) . Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine mini-cluster. Cytogenet. Cell Genet. 74 (4) : 255–8. 2. O'Donovan N, Galvin M, Morgan JG (1999) . Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84 (1-2) : 39–42. 3. Tensen CP, Flier J, Van Der Raaij-Helmer EM, Sampat-Sardjoepersad S, Van Der Schors RC, Leurs R, Scheper RJ, Boorsma DM, Willemze R (1999) . Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3) . J. Invest. Dermatol. 112 (5) : 716–22.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PA1429

14019 MW

34 kDa

No cross reactivity with other proteins.

C-X-C motif chemokine 9

Secreted.

Belongs to the intercrine alpha (chemokine CxC) family.

C-X-C motif chemokine 9

Rabbit IgG

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.