Anti-MINDY3 Antibody Picoband® 0,00647 Vervoeging

The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants.

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

MINDY3

80013

Q9H8M7

Human, Monkey, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human MINDY3 recombinant protein (Position: A52-K396) .

Ubiquitously expressed.

Flow Cytometry

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

1. Liu, B., Liu, Y., Chen, J., Wei, Z., Yu, H., Zhen, Y., Lu, L., Hui, R. CARP is a novel caspase recruitment domain containing pro-apoptotic protein. Biochem. Biophys. Res. Commun. 293: 1396-1404, 2002. 2. Shi, Y., Chen, J., Li, Z., Zhang, Z., Yu, H., Sun, K., Wang, X., Song, X., Wang, Y., Zhen, Y., Yang, T., Lou, K., Zhang, Y., Zhang, G., Hu, Y., Ji, J., Hui, R. C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer. Oncogene 30: 4107-4117, 2011.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

14377 MW

6

Retrotransposon Gag like 10

Cell membrane; Lipid-anchor, GPI-anchor.

Lymphocyte antigen 6A-2/6E-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.