Anti-MIPOL1 Antilichaam Picoband® fluoro594 Vervoeging

MIPOL1 (Mirror Image Polydactyly 1), also known as CCDC193 (Coiled-coil domain containing 193), is a protein that in humans is encoded by the MIPOL1 gene. This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described.

Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9

MIPOL1

145282

Q8TD10

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human MIPOL1 recombinant protein (Position: N63-A399) .

Highly expressed in brain, spleen and peripheral blood leukocytes.

Flow Cytometry

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Liquid

Facilitative glucose transporter; binds cytochalasin B with low affinity.

1. Kamnasaran, D., O'Brien, P. C., Zackai, E. H., Muenke, M., Ferguson-Smith, M. A., Cox, D. W. Rearrangement in the PITX2 and MIOL1 genes in a patient with a t (4;14) chromosome. Europ. J. Hum. Genet. 11: 315-324, 2003. 2. Kondoh, S., Sugawara, H., Harada, N., Matsumoto, N., Ohashi, H., Sato, M., Kantaputra, P. N., Ogino, T., Tomita, H., Ohta, T., Kishino, T., Fukushima, Y., Niikawa, N., Yoshiura, K. A novel gene is disrupted at a 14q13 breakpoint of t (2;14) in a patient with mirror-image polydactyly of hands and feet. J. Hum. Genet. 47: 136-139, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Solute carrier family 2 member 6

Cell membrane. Multi-pass membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.