Anti-MISP Antibody Picoband® 31.0550 Vervoeging

The protein encoded by this gene is an actin-bundling protein involved in determining cell morphology and mitotic progression. The encoded protein is required for the proper positioning of the mitotic spindle. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein; NMA; BAMBI; NMA

MISP

126353

Q8IVT2

Human

No cross-reactivity with other proteins.

E.coli-derived human MISP recombinant protein (Position: M1-R632) .

Expressed in adult liver.

Flow Cytometry

Atherosclerosis, Cardiovascular, Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction

Immunogen affinity purified.

Liquid

Negatively regulates TGF-beta signaling.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 6/26/2013. 2. Maier, B., Kirsch, M., Anderhub, S., Zentgraf, H., Kramer, A. The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells. Cell Cycle 12: 1457-1471, 2013. 3. Zhu, M., Settele, F., Kotak, S., Sanchez-Pulido, L., Ehret, L., Ponting, C. P., Gonczy, P., Hoffmann, I. MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression. J. Cell Biol. 200: 773-787, 2013.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

17136 MW

6

BMP and activin membrane bound inhibitor

Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.