Anti-MLH1 Monoklonale Antilichaam (Kloon:IHC409)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MutL Homolog 1 (MLH1) is a protein involved in the mismatch-repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer, as the MLH1 gene is frequently mutated in patients with this cancer. Use of Anti-MLH1 is optimized when paired in an IHC panel with MSH6, MSH2, and PMS2. Anti-MLH1 is useful in the detection of MLH1 in a number of normal and neoplastic tissues, and for identifying a loss of MLH1 in tumors that are microsatellite-unstable.
MLH1||COCA2
MLH1
4292
P40692
• Mouse
Human
Recombinant Human MLH1
• Monoclonal
IHC409
IHC
Protein A/G Chromatography
Purified
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and
Store at 2°C - 8°C. Do not freeze.
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
Mouse IgG2a
Beschrijving
MutL Homolog 1 (MLH1) is a protein involved in the mismatch-repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer,
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