Anti-MRGX1/MRGPRX1 Antibody Picoband® fluoro550 Vervoeging

MAS-related G-protein coupled receptor, member C, also known as MRGPRC or MRGPRX1, is a human gene. The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of genes, called MrgXs or sensory neuron-specific receptors, of which many fewer appear to be expressed in sensory neurons.

Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 1; Mrgprx1; Mrgc, Mrgprc, Mrgprc11, Snsr, Snsr1

MRGPRX1

282547

Q8R4G1

Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of rat MRGX1.

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors) . .

Flow Cytometry

G Protein Signaling, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Liquid

Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G (q) and G (11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity) . .

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

37074 MW

6

Mas-related G-protein coupled receptor member X1

Cell membrane; Multi-pass membrane protein.

Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Mas-related G-protein coupled receptor member X1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.