Anti-MSL2 Antibody Picoband® 0,00647 Vervoeging

MSL2 (MSL Complex Subunit 2) is a protein coding gene located on human chromosome 3q22.3. MSL2 is also known as MSL-2, MSL2L1 and RNF184. The human MSL2 gene encodes a 62541 Da protein containing 577 amino acids. The MSL2 protein is ubiquitously expressed in bone marrow, lymph node and other tissues. Among its related pathways are Chromatin organization and Chromatin Regulation / Acetylation. MSL2 is related to ligase activity. MSL2 is associated with some diseases, such as Atrial Septal Defect 3.

Short transient receptor potential channel 5; TrpC5; Transient receptor protein 5; TRP-5; hTRP-5; hTRP5; TRPC5; TRP5

MSL2

55167

Q9HCI7

Human

No cross-reactivity with other proteins.

E.coli-derived human MSL2 recombinant protein (Position: M1-C577) .

Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.

Flow Cytometry

Calcium Channels, Calcium Signaling, Metabolism, Neuroscience, Neurotransmission, Plasma Membrane, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Liquid

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/31/2012. 2. Nagase, T., Kikuno, R., Nakayama, M., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 273-281, 2000. 3. Smith, E. R., Cayrou, C., Huang, R., Lane, W. S., Cote, J., Lucchesi, J. C. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Molec. Cell. Biol. 25: 9175-9188, 2005. Note: Erratum: Molec. Cell. Biol. 26: 387 only, 2006.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

91791 MW

6

Transient receptor potential cation channel subfamily C member 5

Cell membrane. Multi-pass membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.