Anti-MSL2 Antibody Picoband®

MSL2 (MSL Complex Subunit 2) is a protein coding gene located on human chromosome 3q22.3. MSL2 is also known as MSL-2, MSL2L1 and RNF184. The human MSL2 gene encodes a 62541 Da protein containing 577 amino acids. The MSL2 protein is ubiquitously expressed in bone marrow, lymph node and other tissues. Among its related pathways are Chromatin organization and Chromatin Regulation / Acetylation. MSL2 is related to ligase activity. MSL2 is associated with some diseases, such as Atrial Septal Defect 3.

Boster Bio Anti-MSL2 Antibody Picoband® catalog # A02712-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Short transient receptor potential channel 5; TrpC5; Transient receptor protein 5; TRP-5; hTRP-5; hTRP5; TRPC5; TRP5

MSL2

55167

Q9HCI7

Human

No cross-reactivity with other proteins.

E.coli-derived human MSL2 recombinant protein (Position: M1-C577) .

Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.

ELISA, Flow Cytometry, IF, ICC, WB

Calcium Channels, Calcium Signaling, Metabolism, Neuroscience, Neurotransmission, Plasma Membrane, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/31/2012. 2. Nagase, T., Kikuno, R., Nakayama, M., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 273-281, 2000. 3. Smith, E. R., Cayrou, C., Huang, R., Lane, W. S., Cote, J., Lucchesi, J. C. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Molec. Cell. Biol. 25: 9175-9188, 2005. Note: Erratum: Molec. Cell. Biol. 26: 387 only, 2006.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A02712-1

91791 MW

63 kDa

6

Transient receptor potential cation channel subfamily C member 5

Cell membrane. Multi-pass membrane protein.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.