Anti-MYBPC2 Antilichaam

Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.

Boster Bio Anti-MYBPC2 Antibody (Catalog # A14099) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse.

MYBPC, MYBPCF, Myosin-binding protein C, fast-type, C-protein, skeletal muscle fast isoform, Fast MyBP-C

MYBPC2

Q14324

Human, Mouse

MYBPC2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MYBPC2. The immunogen is located within amino acids 1070 - 1120 of MYBPC2.

ELISA, WB, IHC-P

Homeostasis

MYBPC2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

MYBPC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A14099

128072 MW

Myosin binding protein C, fast type

Chicken

Myosin binding protein C, fast type

IgG

MYBPC2 Antibody is supplied in PBS containing 0.02% sodium azide.