Anti-MYL4 Antibody Picoband®

Atrial Light Chain-1 (ALC-1), also known as Essential Light Chain, Atrial is a protein that in humans is encoded by the MYL4 gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Boster Bio Anti-MYL4 Antibody Picoband® catalog # A08496-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

MYL4; MLC1; PRO1957; Myosin light chain 4; Myosin light chain 1, embryonic muscle/atrial isoform; Myosin light chain alkali GT-1 isoform

MYL4

4635

P12829

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequencein the middle region of human MYL4.

WB

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Cohen-Haguenauer, O., Barton, P. J. R., Van Cong, N., Cohen, A., Masset, M., Buckingham, M., Frezal, J. Chromosomal assignment of two myosin alkali light-chain genes encoding the ventricular/slow skeletal muscle isoform and the atrial/fetal muscle isoform (MYL3, MYL4) . Hum. Genet. 81: 278-282, 1989. 2. Orr, N., Arnaout, R., Gula, L. J., Spears, D. A., Leong-Sit, P., Li, Q., Tarhuni, W., Reischauer, S., Chauhan, V. S., Borkovich, M., Uppal, S., Adler, A., Coughlin, S. R., Stainier, D. Y. R., Gollob, M. H. A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation. Nature Commun 7: 11303, 2016. Note: Electronic Article. 3. Seharaseyon, J., Bober, E., Hsieh, C.-L., Fodor, W. L., Francke, U., Arnold, H.-H., Vanin, E. F. Human embryonic/atrial myosin alkali light chain gene: characterization, sequence and chromosomal location. Genomics 7: 289-293, 1990.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A08496-2

22 kDa

24 kDa

Myosin light chain 4

Myosin light chain 4

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.