Anti-NAC-1 NACC1 Monoklonale Antilichaam

Boster Bio Anti-NAC-1 NACC1 Monoclonal Antibody catalog # A08675. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Nucleus accumbens-associated protein 1; NAC-1; BTB/POZ domain-containing protein 14B; NACC1; BTBD14B, NAC1

NACC1

Q96RE7

Human

Purified recombinant fragment of human NAC-1 expressed in E. Coli.

Clone: 6H2

Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer. .

WB, IHC, IF, ELISA

Ascitic fluid

1 mg/mL

Liquid

Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08675

57258 MW

Nucleus accumbens-associated protein 1

Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation. .

Ascitic fluid containing 0.03% sodium azide.