Anti-Nac1/NACC1 Antibody Picoband® fluoro594 Vervoeging

Nucleus accumbens-associated protein 1 is a protein that in humans is encoded by the NACC1 gene. This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9.

Annexin A8 ; Annexin VIII ; Annexin-8 ; Vascular anticoagulant-beta ; VAC-beta ; ANXA8 ; ANX8

NACC1

112939

Q96RE7

Human

No cross-reactivity with other proteins.

E.coli-derived human Nac1/NACC1 recombinant protein (Position: E114-E317) .

Ubiquitously expressed.

Flow Cytometry

Signal Transduction, Cardiovascular, Cytoskeleton, Cytoskeleton/ECM, Actin Binding Proteins, Actin, etc., Microfilaments, Cell Adhesion

Immunogen affinity purified.

Liquid

This protein is an anticoagulant protein that acts as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

1. Cha, X. Y., Pierce, R. C., Kalivas, P. W., Macker, S. A. NAC-1, a rat brain mRNA, is increased in the nucleus accumbens three weeks after chronic cocaine self-administration. J. Neurosci. 17: 6864-6871, 1997. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/13/2017. 3. Korutla, L., Wang, P. J., Lewis, D. M., Neustadter, J. H., Stromberg, M. F., Mackler, S. A. Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1. Neuroscience 110: 421-429, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

36881 MW

6

Annexin A8

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Annexin A8

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.