Anti-NANP Antibody Picoband® fluoro594 Vervoeging

NANP (N-acylneuraminate-9-phosphatase), also known as HDHD4 (Haloacid dehalogenase-like hydrolase domain-containing protein 4), is a 248 amino acid protein that belongs to the haloacid dehalogenase (HAD) family and is responsible for dephosphorylating Neu5Ac-9-phosphate to form N-acetylneuraminate. Characteristic of the HAD phosphatase family, the catalytic activity of NANP is dependent upon the presence of magnesium and is inhibited by vanadate and calcium.

One cut domain family member 2; Hepatocyte nuclear factor 6-beta; HNF-6-beta; One cut homeobox 2; Transcription factor ONECUT-2; OC-2; ONECUT2; HNF6B

NANP

140838

Q8TBE9

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human NANP recombinant protein (Position: R5-M246) .

Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.

Flow Cytometry

Epigenetics and Nuclear Signaling, Transcription, Transcription Factors

Immunogen affinity purified.

Liquid

Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.

1. Maliekal, P., Vertommen, D., Delpierre, G., Van Schaftingen, E. Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase. Glycobiology 16: 165-172, 2006.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

One cut homeobox 2

Nucleus.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.