Anti-NARFL/CIAO3 Antibody Picoband® Biotin Conjugated

Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Involved in several processes, including intracellular oxygen homeostasis; iron-sulfur cluster assembly; and response to hypoxia. Part of cytosolic [4Fe-4S] assembly targeting complex.

CIAO3; NARFL; PRN; Cytosolic iron-sulfur assembly component 3; Cytosolic Fe-S cluster assembly factor NARFL; Iron-only hydrogenase-like protein 1; IOP1; Nuclear prelamin A recognition factor-like protein; Protein related to Narf

CIAO3

64428

Q9H6Q4

Human

No cross-reactivity with other proteins

E.coli-derived human NARFL/CIAO3 recombinant protein (Position: Y196-W476) . Human NARFL/CIAO3 shares 88.3% and 86.8% amino acid (aa) sequence identity with mouse and rat NARFL/CIAO3, respectively.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/19/2011. 2. Huang, J., Song, D., Flores, A., Zhao, Q., Mooney, S. M., Shaw, L. M., Lee, F. S. IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1-alpha activity. Biochem. J. 401: 341-352, 2007. 3. Song, D., Lee, F. S. Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis. J. Biol. Chem. 286: 15797-15805, 2011.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

53 kDa

Cytosolic iron-sulfur assembly component 3

Cytosolic iron-sulfur assembly component 3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.