Anti-NCF1 Konijn Monoklonale Antilichaam

Boster Bio Anti-NCF1 Rabbit Monoclonal Antibody catalog # M01586. Tested in WB, IP applications. This antibody reacts with Human.

Claudin-1; Senescence-associated epithelial membrane protein; CLDN1; CLD1, SEMP1; UNQ481/PRO944

NCF1

653361

P14598

Human

A synthesized peptide derived from human NCF1

Clone: 23N68

Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. .

WB, IP

Cell Adhesion, Cytoskeleton/ECM, Signal Transduction, Tight Junctions

Affinity-chromatography

0.5mg/ml

Liquid

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an in effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01586

22744 MW

47 kDa

Claudin-1

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Lysosome-associated membrane glycoprotein 2 (Lamp2)

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.