Anti-NCOA4 Antibody Picoband® fluoro550 Vervoeging

Nuclear receptor coactivator 4 is a protein that in humans is encoded by the NCOA4 gene. This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Urokinase-type plasminogen activator; U-plasminogen activator; uPA; Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B; PLAU

NCOA4

8031

Q13772

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human NCOA4 recombinant protein (Position: R14-M614) .

Expressed in the prostate gland and prostate cancers.

Flow Cytometry

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells

Immunogen affinity purified.

Liquid

Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

1. Entrez Gene: NCOA4 Nuclear receptor coactivator 4. 2. Santoro M, Dathan NA, Berlingieri MT, Bongarzone I, Paulin C, Grieco M, Pierotti MA, Vecchio G, Fusco A (Feb 1994) . Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma. Oncogene. 9 (2) : 509–16. 3. Yeh S, Chang C (May 1996) . Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proceedings of the National Academy of Sciences of the United States of America. 93 (11) : 5517–21.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Plasminogen activator, urokinase

Secreted.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.