Anti-NDST4 Antibody Picoband®

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity) .

Boster Bio Anti-NDST4 Antibody Picoband® catalog # A11749-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24

NDST4

64579

Q9H3R1

Human

No cross-reactivity with other proteins.

E.coli-derived human NDST4 recombinant protein (Position: Q39-L260) .

Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

WB, Flow Cytometry, ELISA

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

1. Aikawa, J., Grobe, K., Tsujimoto, M., Esko, J. D. Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase: structure and activity of the fourth member, NDST4. J. Biol. Chem. 276: 5876-5882, 2001.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A11749-1

101 kDa

6

Eva-1 homolog A, regulator of programmed cell death

Endoplasmic reticulum membrane, Single-pass membrane protein, Lysosome membrane.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.