Anti-NDUFA4 Antibody Picoband® 0,00647 Vervoeging

NDUFA4, mitochondrial complex associated is a protein that in humans is encoded by the NDUFA4 gene. The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Interleukin 1 family member 10 ; Interleukin 1 family, member 10 (Predicted) ; Il1f10 ; Il1f10_predicted ; rCG_45898

NDUFA4

4697

O00483

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human NDUFA4 recombinant protein (Position: M1-F81) .

Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

Flow Cytometry

Cytokines, Immunology, Innate Immunity, Interleukins

Immunogen affinity purified.

Liquid

Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS) . Ligand for IL-36R/IL1RL2.

1. Zhang, Y. , Ge, M. , Chen, Y. , Yang, Y. , Chen, W. , & Wu, D. , et al. (2022) . Ndufa4 promotes cell proliferation by enhancing oxidative phosphorylation in pancreatic adenocarcinoma. Journal of Bioenergetics and Biomembranes, 54 (5), 283-291. 2. Xu, W. , Lai, Y. , Pan, Y. , Tan, M. , Ma, Y. , & Sheng, H. , et al. M6a rna methylation-mediated ndufa4 promotes cell proliferation and metabolism in gastric cancer. Cell Death & Disease. 3. Ramzan, R. , Rhiel, A. , Weber, P. , Kadenbach, B. , & Vogt, S. . (2019) . Reversible dimerization of cytochrome c oxidase regulates mitochondrial respiration. Mitochondrion, 49.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

17081 MW

6

Interleukin 1 family member 10 (theta)

Secreted .

Nck-associated protein 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.