Anti-NDUFAF4 Antibody Picoband®

NADH:ubiquinone oxidoreductase complex assembly factor 4, (NDUFAF4) also known as Hormone-regulated proliferation-associated protein of 20 kDa, (HRPAP20) or C6orf66 is a protein that in humans is encoded by the NDUFAF4 gene. NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency.

Boster Bio Anti-NDUFAF4 Antibody Picoband® catalog # A11650-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24

NDUFAF4

29078

Q9P032

Human

No cross-reactivity with other proteins.

E.coli-derived human NDUFAF4 recombinant protein (Position: K24-K175) .

Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

1. Baertling, F., Sanchez-Caballero, L., van den Brand, M. A. M., Wintjes, L. T., Brink, M., van den Brandt, F. A., Wilson, C., Rodenburg, R. J. T., Nijtmans, L. G. J. NDUFAF4 variants are associated with Leigh syndrome and cause a specific mitochondrial complex I assembly defect. Europ. J. Hum. Genet. 25: 1273-1277, 2017. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 2/8/2008. 3. Karp, C. M., Pan, H., Zhang, M., Buckley, D. J., Schuler, L. A., Buckley, A. R. Identification of HRPAP20: a novel phosphoprotein that enhances growth and survival in hormone-responsive tumor cells. Cancer Res. 64: 1016-1025, 2004.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A11650-1

21 kDa

6

Eva-1 homolog A, regulator of programmed cell death

Endoplasmic reticulum membrane, Single-pass membrane protein, Lysosome membrane.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.