Anti-NDUFB7 Antibody Picoband® fluoro594 Vervoeging

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, also known as complex I-B18, is an enzyme that in humans is encoded by the NDUFB7 gene. The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I) . Mammalian complex I is composed of 45 different subunits. It is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

NDUFB7

4713

P17568

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human NDUFB7 recombinant protein (Position: M1-R98) .

Ubiquitous. Highly expressed in brain. .

Flow Cytometry

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

1. Correia, S. P., Moedas, M. F., Naess, K., Bruhn, H., Maffezzini, C., Calvo-Garrido, J., Lesko, N., Wibom, R., Schober, F. A., Jemt, A., Stranneheim, H., Freyer, C., Wedell, A., Wredenberg, A. Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7. Hum. Mutat. 42: 378-384, 2021. 2. Emahazion, T., Beskow, A., Gyllensten, U., Brookes, A. J. Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain. Cytogenet. Cell Genet. 82: 115-119, 1998. 3. Loeffen, J. L. C. M., Triepels, R. H., van den Heuvel, L. P., Schuelke, M., Buskens, C. A. F., Smeets, R. J. P., Trijbels, J. M. F., Smeitink, J. A. M. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. Biochem. Biophys. Res. Commun. 253: 415-422, 1998.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

16 kDa

6

Protein NDRG3

Membrane ; Single-pass type I membrane protein .

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.