Anti-NEDD1 Antibody Picoband® 31.0550 Vervoeging

Neural precursor cell expressed, developmentally down-regulated 1, also known as Nedd1, is a human gened and encodes the protein NEDD1. NEDD1 is required for mitosis progression. NEDD1 promotes the nucleation of microtubules from the spindle. This antibody works well in WB, IHC, IP and IF application.

RasGAP-activating-like protein 1; RAS protein activator like 1

NEDD1

121441

Q8NHV4

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human NEDD1 recombinant protein (Position: D191-E647) .

Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798) . Expressed in melanocytes (PubMed:23999003) .

Flow Cytometry

Cancer, G Protein Signaling, Oncoproteins/Suppressors, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins, Tumor Suppressors

Immunogen affinity purified.

Liquid

Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

1. Kumar, S., Tomooka, Y., Noda, M. Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185: 1155-1161, 1992. 2. Takai, S., Yoshida, Y., Noda, M., Yamada, K., Kumar, S. Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization. Hum. Genet. 95: 96-98, 1995.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

RAS protein activator like 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.