Anti-NEDD8 Konijn Monoklonale Antilichaam

Boster Bio Anti-NEDD8 Rabbit Monoclonal Antibody catalog # M00547. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

NEDD8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; NEDD-8; Ubiquitin-like protein Nedd8; NEDD8

NEDD8

4738

Q15843

Human, Mouse, Rat

A synthesized peptide derived from human NEDD8

Clone: AOAE-14

Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes. .

WB, IHC, ICC, IF, IP

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ub-Like Proteins

Affinity-chromatography

0.5mg/ml

Liquid

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C- APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00547

9072 MW

42 kDa, 48 kDa

NEDD8

Nucleus . Mainly nuclear.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.