Anti-NEK11 Antibody Picoband® 31.0550 Vervoeging

This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.

NEK11; Serine/threonine-protein kinase Nek11; EC 2.7.11.1; Never in mitosis A-related kinase 11; NimA-related protein kinase 11

NEK11

79858

Q8NG66

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human NEK11 recombinant protein (Position: E72-Q630) . Human NEK11 shares 71.1% amino acid (aa) sequence identity with mouse NEK11.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Noguchi, K., Fukazawa, H., Murakami, Y., Uehara, Y. Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses. J. Biol. Chem. 277: 39655-39665, 2002. 2. Noguchi, K., Fukazawa, H., Murakami, Y., Uehara, Y. Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. J. Biol. Chem. 279: 32716-32727, 2004.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

74 kDa

6

NIMA related kinase 11

Serine/threonine-protein kinase Nek11

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.