Anti-NEK7 Antibody Picoband® 0,00647 Vervoeging

NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.

NEK7; Serine/threonine-protein kinase Nek7; EC 2.7.11.1; Never in mitosis A-related kinase 7; NimA-related protein kinase 7

NEK7

140609

Q8TDX7

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human NEK7 recombinant protein (Position: M1-S302) . Human NEK7 shares 97.7% and 98% amino acid (aa) sequence identity with mouse and rat NEK7, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. He, Y., Zeng, M. Y., Yang, D., Motro, B., Nunez, G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature 530: 354-357, 2016. 2. Kimura, M., Okano, Y. Identification and assignment of the human NIMA-related protein kinase 7 gene (NEK7) to human chromosome 1q31.3. Cytogenet. Cell Genet. 94: 33-38, 2001. 3. Sharif, H., Wang, L., Wang, W. L., Magupalli, V. G., Andreeva, L., Qiao, Q., Hauenstein, A. V., Wu, Z., Nunez, G., Mao, Y., Wu, H. Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. Nature 570: 338-343, 2019.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

35 kDa

6

NIMA related kinase 7

Serine/threonine-protein kinase Nek7

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.