Anti-NETO1 Antilichaam

Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.

Boster Bio Anti-NETO1 Antibody (Catalog # A08303) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

BCTL1, BTCL1, Neuropilin and tolloid-like protein 1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1

NETO1

Q8TDF5

Human, Mouse, Rat

NETO1 antibody is predicted to not cross-react with other NETO protein family members.

NETO1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NETO1. The immunogen is located within amino acids 350 - 400 of NETO1.

ELISA, WB, IHC-P, IF

Neuroscience

NETO1 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D- aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (By similarity) . .

NETO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A08303

60191 MW

Neuropilin (NRP) and tolloid (TLL) -like 1

Isoform 2: Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Component of the postsynaptic density (PSD) of excitatory synapses. .

Neuropilin (NRP) and tolloid (TLL) -like 1

IgG

NETO1 Antibody is supplied in PBS containing 0.02% sodium azide.