Anti-neurgonadotrofine-3 (NT-3) Antilichaam

NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.

Our Anti-Neurotrophin-3 (NT-3) rabbit polyclonal primary antibody detects chicken, human, and rat Neurotrophin-3 (NT-3), and is affinity-purified. It is validated for use in ELISA, IHC-Frozen, Neutralize, WB.

Our Anti-Neurotrophin-3 (NT-3) rabbit polyclonal primary antibody detects chicken, human, and rat Neurotrophin-3 (NT-3), and is affinity-purified. It is validated for use in ELISA, IHC-Frozen, Neutralization, WB.

Neurotrophin-3; Neurotrophic factor; HDNF; Nerve growth factor 2; NGF-2; Ntf3; Ntf-3

P20783

Chicken, Human, and Rat

A synthetic peptide (YAEHKSHRGEY) as part of human (aa: 139-149), mouse and rat NT3 protein conjugated to BSA has been used as the immunogen.

Neurotrophin-3 (NT-3)

Unconjugated

ELISA, IHC-Frozen, Neutralize, WB

Affinity-purified

Lyophilized from a solution containing PBS pH 7.4

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 20 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

1-10 μg/mL

1-10 μg/mL

A cross reactivity of less than 0.1% to mouse NGF, recombinant human BDNF and NT4/5 has been shown by dot blot. This antiserum is known to react with rat, chicken and human NT3.

Rabbit

Lyophilized

IgG

Human