Anti-NeuroD1 Konijn Monoklonale Antilichaam

Boster Bio Anti-NeuroD1 Rabbit Monoclonal Antibody catalog # M01038. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Neurogenic differentiation factor 1; NeuroD; NeuroD1; Class A basic helix-loop-helix protein 3; bHLHa3; NEUROD1; BHLHA3, NEUROD

NEUROD1

4760

Q13562

Human, Mouse, Rat

A synthesized peptide derived from human NeuroD1

Clone: AAFI-14

Ubiquitous. .

WB, IP

Atherosclerosis, Cancer, Cardiovascular, Cell Type Marker, Diabetes, Diabetes-associated, Domain Families, Epigenetics and Nuclear Signaling, Heart Disease, Hlh/Leucine Zipper, Metabolism, Neurogenesis, Neurology Process, Neuroscience, Transcription

Affinity-chromatography

0.5mg/ml

Liquid

Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01038

39920 MW

38-60 kDa

Neurogenic differentiation factor 1

Cytoplasm . Nucleus . In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity) . Colocalizes with NR0B2 in the nucleus. .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.