Anti-Neuronale pentraxine-2 NPTX2 Antilichaam

Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson's disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD. This NPTX2 antibody is predicted to be specific to NPTX2 and not recognize NPTX1.

Boster Bio Anti-Neuronal pentraxin-2 NPTX2 Antibody (Catalog # A09667) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

NP2, NARP, NP-II, Neuronal pentraxin-2, Neuronal pentraxin II, NP2

NPTX2

P47972

Human, Mouse, Rat

Anti-NPTX2 antibody was raised against a peptide corresponding to 16 amino acids near the center of human NPTX2. The immunogen is located within amino acids 170 - 220 of NPTX2.

Ubiquitous.

ELISA, WB, IHC-P, IF

Neuroscience

NPTX2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity) . .

NPTX2 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A09667

47042 MW

Neuronal pentraxin II

Secreted .

Guinea Pig

Neuronal pentraxin II

IgG

NPTX2 Antibody is supplied in PBS containing 0.02% sodium azide.