Anti-NNMT Antibody Picoband® 31.0550 Vervoeging

Nicotinamide N-methyltransferase (NNMT) is an enzyme that in humans is encoded by the NNMT gene. N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.

NNMT

4837

P40261

Human, Mouse, Rat

E.coli-derived human NNMT recombinant protein (Position: K8-L264) . Human NNMT shares 85.1% amino acid (aa) sequence identity with mouse NNMT.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Aksoy, S., Brandriff, B. F., Ward, A., Little, P. F. R., Weinshilboum, R. M. Human nicotinamide N-methyltransferase gene: molecular cloning, structural characterization and chromosomal localization. Genomics 29: 555-561, 1995. 2. Aksoy, S., Szumlanski, C. L., Weinshilboum, R. M. Human liver nicotinamide N-methyltransferase: cDNA cloning, expression, and biochemical characterization. J. Biol. Chem. 269: 14835-14840, 1994. 3. Eckert, M. A., Coscia, F., Chryplewicz, A., Chang, J. W., Hernandez, K. M., Pan, S., Tienda, S. M., Nahotko, D. A., Li, G., Blazenovic, I., Lastra, R. R., Curtis, M., Yamada, S. D., Perets, R., McGregor, S. M., Andrade, J., Fiehn, O., Moellering, R. E., Mann, M., Lengyel, E. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature 569: 723-728, 2019.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.