Anti-NOC2L Antilichaam

Boster Bio Anti-NOC2L Antibody (Catalog# A11194) . Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

NOC2L; NIR; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; NOC2-like protein; Novel INHAT repressor

NOC2L

Q9Y3T9

Human, Mouse, Rat

A peptide derived from human NOC2L. Immunogen sequence location: 602-651

WB, IHC, ICC, IF, ELISA

Acetylation, Apoptosis, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Chromatin Modifying Enzymes, Co-Factors, Epigenetics and Nuclear Signaling, Intracellular, p53 Pathway, Transcription

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Liquid

Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC) -independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A11194

84919 MW

Nucleolar complex protein 2 homolog

Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin- D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.

Rabbit IgG

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.