Anti-NOXA1 Antibody Picoband® fluoro488 Vervoeging

NADPH oxidase activator 1 is an enzyme that in humans is encoded by the NOXA1 gene. This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain. Interaction between the encoded protein and proteins in the oxidase regulatory complex occur via the tetratricopeptide domains. Multiple transcript variants encoding different isoforms have been found for this gene.

NOXA1

10811

Q86UR1

Human

E.coli-derived human NOXA1 recombinant protein (Position: A38-Q434) . Human NOXA1 shares 60.3% and 61% amino acid (aa) sequence identity with mouse and rat NOXA1, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Ambasta, R. K., Schreiber, J. G., Janiszewski, M., Busse, R., Brandes, R. P. Noxa1 is a central component of the smooth muscle NADPH oxidase in mice. Free Radic. Biol. Med. 41: 193-201, 2006. 2. Banfi, B., Clark, R. A., Steger, K., Krause, K.-H. Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. J. Biol. Chem. 278: 3510-3513, 2003. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 7/25/2007.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

51 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.