Anti-NR1/NDOR1 Antibody Picoband® fluoro647 Vervoeging

NADPH-dependent diflavin oxidoreductase 1 is an enzyme that in humans is encoded by the NDOR1 gene. This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein catalyzes the transfer of electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants.

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

NDOR1

27158

Q9UHB4

Human

No cross-reactivity with other proteins.

E.coli-derived human NR1/NDOR1 recombinant protein (Position: R31-Q407) .

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Flow Cytometry

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Immunogen affinity purified.

Liquid

Plays a role in B-cell proliferation and differentiation.

1. Kwasnicka, D. A., Krakowiak, A., Thacker, C., Brenner, C., Vincent, S. R. Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-ed hydrolase, DCS-1. J. Biol. Chem. 278: 39051-39058, 2003. 2. Kwasnicka-Crawford, D. A., Vincent, S. R. Role of a novel dual flavin reductase (NR1) and an associated histidine triad protein (DCS-1) in menadione-induced cytotoxicity. Biochem. Biophys. Res. Commun. 336: 565-571, 2005. 3. Paine, M. J. I., Garner, A. P., Powell, D., Sibbald, J., Sales, M., Pratt, N., Smith, T., Tew, D. G., Wolf, C. R. Cloning and characterization of a novel human dual flavin reductase. J. Biol. Chem. 275: 1471-1478, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

CD72 molecule

Membrane; Single-pass type II membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.