Anti-NSUN6 Antilichaam Picoband® 31.0550 Vervoeging

Enables tRNA (cytidine-5-) -methyltransferase activity and tRNA binding activity. Involved in tRNA C5-cytosine methylation. Located in cytoplasm. Implicated in autosomal recessive intellectual developmental disorder 82.

NSUN6; NOPD1; tRNA; cytosine (72-C (5-methyltransferase NSUN6; EC 2.1.1.-; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family member 6

NSUN6

221078

Q8TEA1

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human NSUN6 recombinant protein (Position: E40-E400) . Human NSUN6 shares 82.3% amino acid (aa) sequence identity with mouse NSUN6.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Chi, L., Delgado-Olguin, P. Expression of NOL1/NOP2/sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis. Gene Expr. Patterns 13: 319-327, 2013. 2. Gross, M. B. Personal Communication. Baltimore, Md. 11/10/2016. 3. Haag, S., Warda, A. S., Kretschmer, J., Gunnigmann, M. A., Hobartner, C., Bohnsack, M. T. NSUN6 is a human RNA methyltransferase that catalyzes formation of m (5) C72 in specific tRNAs. RNA 21: 1532-1543, 2015.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

52 kDa

6

NOP2/Sun RNA methyltransferase 6

TRNA (cytosine (72) -C (5) ) -methyltransferase NSUN6

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.